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Depression Medicine: Special Warnings about Elavil (amitriptyline)
Special concerns with depression medicines
such as Elavil (amitriptyline):
As with most depression medicines, you should not
stop taking elavil
(amitriptyline) abruptly, especially if you have been taking
large doses for a long time. Your doctor probably will want to decrease your
dosage gradually. This will
help prevent possible relapse and will reduce the
possibility of withdrawal symptoms from this depression medicine.
Some other concerns when taking this depression
medicine include that it may make your skin more sensitive to sunlight. Try to
stay out of the sun, wear protective clothing, and apply a sunblock. Also,
elavil (amitryptyline) may cause you to become drowsy or less alert; therefore,
you should not drive or operate dangerous machinery or participate in any
hazardous activity that requires full mental alertness until you know how this
drug effects you. While taking this depression medication, you may feel dizzy or
lightheaded or actually faint when getting up from a lying or sitting position.
If getting up slowly doesn’t help or if this problem continues, notify your
doctor.
Use Elavil with caution if you
have ever had seizures, urinary retention, glaucoma or other chronic eye
conditions, a heart or circulatory system disorder, or liver problems. Be
conscious, too, if you are receiving thyroid medication. You should discuss all
of your medical problems with your doctor before starting any depression
medicine.
Before having surgery, dental treatment, or any
diagnostic procedure, tell the doctor that you are taking Elavil. Certain drugs used during surgery such as anesthetics and muscle
relaxants, and drugs used in certain diagnostic procedures may react badly with Elavil.
Possible food and drug
interactions while taking this depression medicine:
Elavil may intensify the effects
of alcohol. Do not drink alcohol when taking this depression medicine. If Elavil
is taken with certain other drugs, the effects of either could be increased,
decreased, or altered. It is especially important that you consult with your
doctor before taking Elavil in combination with the following:
- Airway-opening drugs such as Sudafed and
Proventil
- Antidepressants that raise serotonin levels
- Other antidepressants, such as amoxapine
- Antihistamines such as Benadryl and Tavist
- Barbiturates such as Phenobarbital
- Certain blood-pressure medicines such as Catapres
- Cimetadine (Tagamet)
- Disulfirum (Antabuse)
- Drugs that control spasms, such as Bentyl and
Donnatal
- Estrogen drugs such as Premarin and oral
contraceptives
- Ethchlorvynol (Placidyl)
- Major tranquilizers such as Mellaril and
Thorazine
- MAO inhibitors, such as Nardil and Parnate
- Medications for irregular heartbeat, such as
Tambocor and Rythmol
- Painkillers such as Demerol and Percocet
- Parkinsonism drugs such as Cogentin and Laradopa
- Quinidine (Quinidex)
- Seizure medications such as Tegretol and Dilantin
- Sleep medicines such as Halcion and Dalmane
- Thyroid hormones (Synthroid)
- Tranquilizers such as Librium and Xanax
- Warfarin (Coumadin)
Special information on this
depression medicine if you’re pregnant or breast-feeding:
The effects of Elavil during
pregnancy have not been adequately studied. If you are pregnant or planning to
become pregnant, inform your doctor immediately. This depression medicine
appears in breast milk. If Elavil is essential to your health,
your doctor may invite you to discontinue breast-feeding until your treatment is
finished.

Information provided by
The PDR Pocket Guide to Prescription Drugs - Sixth Edition
Information and webpage by
Paul Susic
MA Licensed Psychologist Ph.D.
Candidate
(Health and Geriatric Psychologist
Additional pictures of Elavil
dosages
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