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Cymbalta Side Effects and Medication Interactions 

Cymbalta Side Effects of This Antidepressant:

20 mg Cymbalta dosageCymbalta side effects cannot really be anticipated, but if any develop or intensify you should contact your doctor as soon as possible. Only your physician can determine if the Cymbalta side effects make continuing this antidepressant prohibitive. 

Cymbalta side effects may include: 

Appetite changes, constipation, diarrhea, dizziness, dry mouth, fatigue, headache, insomnia, nausea, sexual difficulties, sleepiness, sweating, tremor, urinary difficulties, vomiting, or weakness. 

Potential Interactions With Other Medications and Food

You should never take Cymbalta with other antidepressants called MAO inhibitors such as Nardil, Parnate and Marplan. Also, this medication should never be taken with the drug thioridazine (Mellaril).  You should always talk to your doctor first before taking drugs that act on the central nervous system such as antipsychotics, narcotic painkillers, sleep inducers or tranquilizers. 

You should not take the antidepressant cymbalta if you drink alcohol more than occasionally. 

 

When cymbalta is taken with certain other drugs, the effects can either be increased, decreased or altered in some other way.  It is especially important to check with your physician before taking this antidepressant with any of the following: 

  • Antibiotics known as quinolones, such as Cipro, Floxin, and Trovan

  • Antidepressants known as tricyclics, including Elavil, Pamelor, and Tofranil

  • Antidepressants that raise serotonin levels such as Effexor, Paxil, Prozac, and Zoloft

  • Antipsychotic medications known as phenothiazines, including Compazine, Prolixin, Serentil, Thorazine, Trilafon

  • Flecainide (Tambocor)

  • Fluvoxamine

  • Propafenone (Rythmol)

  • Quinidine 

Some additional cymbalta side effects and reasons this antidepressant should not be prescribed: 

You should not use cymbalta or any other antidepressant for that matter, if it causes an allergic reaction.  In addition, you should not take this depression medication if you have such cymbalta side effects as narrow angle glaucoma, a disease that causes increased pressure in the eyes. 

Absolutely never combine cymbalta with an MAO inhibitor such as Marplan, Nardil or Parnate.  Also, a very serious side effect of cymbalta may occur if you take the drug thioridazine (Mellaril) with Cymbalta, as it could cause fatal heartbeat irregularities. However, this list should never be construed to be a total, complete list of every, or all, Cymbalta side effects.

Information adapted from The PDR Pocket Guide to Prescription Drugs - Sixth Edition

Information and webpage by Paul Susic  MA Licensed Psychologist   Ph.D. Candidate  (Health and Geriatric Psychologist) 

Pictures of several Cymbalta dosages by Permission of Drugs.Com

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Mental Health Diagnosis - DSM-IV Diagnosis and Codes: In Alphabetical Order and Other Antidepressant Info.

Celexa 

Effexor

 Elavil

Lexapro

Luvox

Paxil

Pristiq

Prozac

Remeron  

Trazodone

Wellbutrin 

Zoloft 

 


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