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Cymbalta: A Great New Antidepressant?

Brand Name: Cymbalta                                                                          Generic Name: Duloxetine Hydrochloride 

Cymbalta: Why is this new antidepressant prescribed? 

60 mg Cymbalta dosageCymbalta is a new antidepressant, usually prescribed for treatment of major depression.  Major depression is a very intense, serious and overwhelming feeling of depression that interferes with an individual's daily functioning.  Cymbalta and similar new antidepressants are used to treat symptoms which include major changes in appetite or sleep habits, lack of interest in social or work life, feelings of sadness, worthlessness or guilt, fatigue, difficulty concentrating, difficulty making decisions and for suicidal ideation or attempts. 

Cymbalta is relatively unique compared to other new antidepressants in that is also used to treat diabetic peripheral neuropathy, a painful nerve disorder associated with diabetes that affects the hands legs and also the feet. 

Antidepressants such as Cymbalta are thought to work by correcting an imbalance in the brain chemicals which are known to influence mood, serotonin and norepinephrine.  It belongs in the class of antidepressants referred to as selective serotonin and norepinephrine reuptake inhibitors. 

 

What are some important things to know about Cymbalta? 

Cymbalta may result in some very serious and sometimes fatal reactions when taken with such antidepressants as MAO inhibitors, which includes Marplan, Nardil and Parnate.  You should absolutely never take Cymbalta with these depression medications, and most physicians recommend that you wait at least 14 days after stopping an MAO inhibitor before starting treatment with Cymbalta.  Likewise, before starting on an MAO inhibitor, most doctors usually request that you stop Cymbalta for at least five days before starting antidepressant treatment with an MAO inhibitor. 

Cymbalta: How should this antidepressant be taken? 

You should take Cymbalta at about the same time every day.  You should not chew the tablet or break it open but should swallow it whole.  It may be taken with or without food. 

It may take as much as several weeks for the medication to began to work. Also, you should continue taking the medication even after you begin to feel better.  Do not stop taking this drug without your doctor's approval. Abruptly stopping treatment may cause severe side effects.

Information provided by The PDR Pocket Guide to Prescription Drugs - Seventh Edition

Pictures of several Cymbalta dosages by Permission of Drugs.Com

Information and webpage by Paul Susic  MA Licensed Psychologist   Ph.D. Candidate  (Health and Geriatric Psychologist)   

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