ADHD drugs:
How effective are the stimulant medications?
ADHD drugs and the
stimulants:
Since they were first
accidentally discovered (1937), the most successful development of
ADHD drugs has included the stimulants. Since then, they have
received an enormous amount of research - far more than any other
known treatment for childhood psychiatric disorders. The research
results have overwhelmingly found that these ADHD drugs are quite
effective for the management of ADHD symptoms in most children over
the age of five years old. These medications have not been found to
be quite as effective for children between the ages of four and five
years of age, and are not recommended for children under the age of
three years old. The effectiveness of the stimulant ADHD drugs has
led to their widespread use among children with this condition. It
is now estimated that approximately 2.8% of school-aged children are
being treated with stimulants for their ADHD symptoms. More recent
research continues to find that these medications may be just as
effective for adults and adolescents as they are with children. The
future will probably see increased use of these ADHD drugs with the
older age groups.
ADHD Drugs: The most
common ones
The most commonly
prescribed ADHD drugs are methylphenidate (Ritalin), d-amphetamine (Dexadrine),
and pemoline (Cylert). Adderal has also been approved for the
management of ADHD symptoms. It is a combination of amphetamines,
that is reported by the manufacture to be significantly effective in
the treatment of ADHD symptoms. Because of its similarity between
the previously studied compounds of d-amphetamine and l-amphetamine,
there is no reason to believe that it will not prove to be just as
effective as these other ADHD drugs.
As of this
report, methylphenidate (Ritalin) and d- amphetamine (Cylert) were
the most commonly prescribed ADHD drugs. They act relatively quickly
producing effects on children within 30 to 45 minutes after they are
taken orally in their standard preparations, with the effects
peaking within two to four hours. However, their ability to manage
behavior quickly dissipates within three to seven hours, although
small amounts of the medication may remain in their blood system for
up to 24 hours. Because of the medication’s short half-life (time
that it remains in the blood system), it is frequently prescribed
in
twice or three times daily doses. Although they were once
predominantly used for school days, there has been a recent trend
toward using these ADHD drugs also during school vacations,
especially if the children have severe ADHD or conduct disorder
problems. This is probably due to the fact that the use of these
medications is now believed to not seriously affect a child's growth
as they were previously believed, resulting in the recognition that
the need for medication holidays is probably no longer justified.
Both Ritalin and Dexadrine come in slow release preparations that
may reduce the number of daily doses children require to manage
their ADHD symptoms. Pemoline, in its slow release form, has also
found some modest popularity among ADHD children. However, recent
reports of liver functioning problems in children, and occasionally
death due to such dysfunctioning, have led the manufacture to issue
a warning to physicians that this ADHD drug (Pemoline) should no
longer be considered a first-line agent in the management of
ADHD symptoms.
Information from
Treatment of Childhood Disorders by Eric J. Marsh and Russell A.
Barkley